Agonist-Specific Recruitment of Arrestin Isoforms Differentially Modify Delta Opioid Receptor Function

Ligand-specific recruitment of arrestins facilitates functional selectivity of G-protein-coupled receptor signaling. Here, we describe agonist-selective recruitment of different arrestin isoforms to the delta opioid receptor in mice. A high-internalizing delta opioid receptor agonist (SNC80) prefere...

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Vydáno v:J Neurosci
Hlavní autoři: Pradhan, Amynah A., Perroy, Julie, Walwyn, Wendy M., Smith, Monique L., Vicente-Sanchez, Ana, Segura, Laura, Bana, Alia, Kieffer, Brigitte L., Evans, Christopher J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804011/
https://ncbi.nlm.nih.gov/pubmed/27013682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4124-15.2016
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