Incorporating a Genetic Risk Score into Coronary Heart Disease Risk Estimates: Effect on LDL Cholesterol Levels (the MIGENES Clinical Trial)

BACKGROUND: Whether knowledge of genetic risk for coronary heart disease (CHD) affects health-related outcomes is unknown. We investigated whether incorporating a genetic risk score (GRS) in CHD risk estimates lowers low-density lipoprotein cholesterol (LDL-C) levels. METHODS AND RESULTS: Participan...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Circulation
मुख्य लेखकों: Kullo, Iftikhar J., Jouni, Hayan, Austin, Erin E., Brown, Sherry-Ann, Kruisselbrink, Teresa M., Isseh, Iyad N., Haddad, Raad A., Marroush, Tariq S., Shameer, Khader, Olson, Janet E., Broeckel, Ulrich, Green, Robert C., Schaid, Daniel J., Montori, Victor M., Bailey, Kent R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2016
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803581/
https://ncbi.nlm.nih.gov/pubmed/26915630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.115.020109
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