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Osteoporosis induced in mice by overproduction of interleukin 4.

Osteoporosis is a common disease in which loss of bone mass results in skeletal fragility. The development of therapies for this disorder has been hampered by the lack of a convenient animal model. Here we describe a disorder in bone homeostasis in transgenic mice that inappropriately express the cy...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Lewis, D B, Liggitt, H D, Effmann, E L, Motley, S T, Teitelbaum, S L, Jepsen, K J, Goldstein, S A, Bonadio, J, Carpenter, J, Perlmutter, R M
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1993
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48035/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8265598/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.24.11618
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