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Systematic Survey of Serine Hydrolase Activity in Mycobacterium tuberculosis Defines Changes Associated with Persistence

The transition from replication to non-replication underlies much of Mycobacterium tuberculosis (Mtb) pathogenesis, as non- or slowly replicating Mtb are responsible for persistence and poor treatment outcomes. Therapeutic targeting of non-replicating populations is a priority for tuberculosis treat...

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Detalhes bibliográficos
Publicado no:Cell Chem Biol
Main Authors: Ortega, Corrie, Anderson, Lindsey N., Frando, Andrew, Sadler, Natalie C., Brown, Robert W., Smith, Richard D., Wright, Aaron T., Grundner, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803444/
https://ncbi.nlm.nih.gov/pubmed/26853625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2016.01.003
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