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An Engineered Endomorphin-2 Gene for Morphine Withdrawal Syndrome

An optimal therapeutics to manage opioid withdrawal syndrome is desired for opioid addiction treatment. Down-regulation of endogenous endomorphin-2 (EM2) level in the central nervous system after continuous morphine exposure was observed, which suggested that increase of EM2 could be an alternative...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Wu, Fei-xiang, He, Yan, Di, Hui-ting, Sun, Yu-ming, Pan, Rui-rui, Yu, Wei-feng, Liu, Renyu
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803333/
https://ncbi.nlm.nih.gov/pubmed/27003293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149877
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