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Assessment of Glial Scar, Tissue Sparing, Behavioral Recovery and Axonal Regeneration following Acute Transplantation of Genetically Modified Human Umbilical Cord Blood Cells in a Rat Model of Spinal Cord Contusion

OBJECTIVE AND METHODS: This study investigated the potential for protective effects of human umbilical cord blood mononuclear cells (UCB-MCs) genetically modified with the VEGF and GNDF genes on contusion spinal cord injury (SCI) in rats. An adenoviral vector was constructed for targeted delivery of...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mukhamedshina, Yana O., Garanina, Ekaterina E., Masgutova, Galina A., Galieva, Luisa R., Sanatova, Elvira R., Chelyshev, Yurii A., Rizvanov, Albert A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803326/
https://ncbi.nlm.nih.gov/pubmed/27003408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151745
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