Metabolic Effects of Long-Term Reduction in Free Fatty Acids With Acipimox in Obesity: A Randomized Trial

CONTEXT: Increased circulating free fatty acids (FFAs) have been proposed to contribute to insulin resistance in obesity. Short-term studies have investigated the effects of acipimox, an inhibitor of hormone-sensitive lipase, on glucose homeostasis, but longer-term studies have not been performed. O...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Makimura, Hideo, Stanley, Takara L., Suresh, Caroline, De Sousa-Coelho, Ana Luisa, Frontera, Walter R., Syu, Stephanie, Braun, Laurie R., Looby, Sara E., Feldpausch, Meghan N., Torriani, Martin, Lee, Hang, Patti, Mary-Elizabeth, Grinspoon, Steven K.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2016
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803166/
https://ncbi.nlm.nih.gov/pubmed/26691888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2015-3696
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