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Clinical outcomes of EGFR-TKI treatment and genetic heterogeneity in lung adenocarcinoma patients with EGFR mutations on exons 19 and 21

BACKGROUND: Epidermal growth factor receptor (EGFR) mutations, including a known exon 19 deletion (19 del) and exon 21 L858R point mutation (L858R mutation), are strong predictors of the response to EGFR tyrosine kinase inhibitor (EGFR-TKI) treatment in lung adenocarcinoma. However, whether patients...

詳細記述

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書誌詳細
出版年:Chin J Cancer
主要な著者: Yu, Jiang-Yong, Yu, Si-Fan, Wang, Shu-Hang, Bai, Hua, Zhao, Jun, An, Tong-Tong, Duan, Jian-Chun, Wang, Jie
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802875/
https://ncbi.nlm.nih.gov/pubmed/27001083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40880-016-0086-2
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