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Structure of developmental gene regulatory networks from the perspective of cell fate-determining genes

The core of gene regulatory networks (GRNs) is formed by transcription factors (TF) and cis–regulatory modules (CRMs) present in their downstream genes. GRNs have a modular structure in which complex circuitries link TFs to CRMs to generate specific transcriptional outputs.(1) Of particular interest...

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Hauptverfasser: Martín, Mercedes, Organista, María F., de Celis, Jose F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802764/
https://ncbi.nlm.nih.gov/pubmed/26735242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541264.2015.1130118
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