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Single-cell lineage tracking analysis reveals that an established cell line comprises putative cancer stem cells and their heterogeneous progeny

Mammalian cell culture has been used in many biological studies on the assumption that a cell line comprises putatively homogeneous clonal cells, thereby sharing similar phenotypic features. This fundamental assumption has not yet been fully tested; therefore, we developed a method for the chronolog...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sato, Sachiko, Rancourt, Ann, Sato, Yukiko, Satoh, Masahiko S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802345/
https://ncbi.nlm.nih.gov/pubmed/27003384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23328
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