The relationship between synthetic and editing functions of the active site of an aminoacyl-tRNA synthetase.

We have analyzed, by site-directed mutagenesis, the molecular basis of the editing function and its relation to the synthetic function of Escherichia coli methionyl-tRNA synthetase. The data obtained fit a model of the active site that partitions an amino acid substrate between synthetic and editing...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Kim, H Y, Ghosh, G, Schulman, L H, Brunie, S, Jakubowski, H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48022/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8265588/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.24.11553
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