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Dissection of transcriptional and cis‐regulatory control of differentiation in human pancreatic cancer

The histological grade of carcinomas describes the ability of tumor cells to organize in differentiated epithelial structures and has prognostic and therapeutic impact. Here, we show that differential usage of the genomic repertoire of transcriptional enhancers leads to grade‐specific gene expressio...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Diaferia, Giuseppe R, Balestrieri, Chiara, Prosperini, Elena, Nicoli, Paola, Spaggiari, Paola, Zerbi, Alessandro, Natoli, Gioacchino
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801945/
https://ncbi.nlm.nih.gov/pubmed/26769127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201592404
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