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Calmodulin activity regulates group I metabotropic glutamate receptor-mediated signal transduction and synaptic depression

Group I metabotropic glutamate receptors (GpI mGluR) including mGluR1 and 5 (mGluR1/5) are coupled to Gq and modulate activity-dependent synaptic plasticity. Direct activation of mGluR1/5 causes protein translation-dependent long-term depression (LTD). Although it has been established that intracell...

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Detalhes bibliográficos
Publicado no:J Neurosci Res
Main Authors: Sethna, Ferzin, Zhang, Ming, Kaphzan, Hanoch, Klann, Eric, Autio, Dawn, Cox, Charles L, Wang, Hongbing
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801747/
https://ncbi.nlm.nih.gov/pubmed/26864654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23719
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