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The pugilist(Dominant) Mutation of Drosophila melanogaster: A Simple-Sequence Repeat Disorder Reveals Localized Transport in the Eye

The pugilist-Dominant mutation results from fusion of a portion of the gene encoding the tri-functional Methylene Tetrahydrofolate Dehydrogenase (E.C.1.5.1.5, E.C.3.5.4.9, E.C.6.3.4.3) to approximately one kb of a heterochromatic satellite repeat. Expression of this fusion gene results in an unusual...

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Udgivet i:PLoS One
Main Authors: Rong, Yikang S., Golic, Mary M., Golic, Kent G.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801370/
https://ncbi.nlm.nih.gov/pubmed/26999432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151377
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