Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II.
The transcriptional activation of eukaryotic class II genes by sequence-specific regulatory proteins requires cofactors in addition to the general transcription factors. One cofactor (termed PC3) was purified from HeLa cells and identified by sequence analysis and functional assays as human DNA topo...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48013/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8265582/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.24.11508 |
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