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Inactivation of 3-hydroxybutyrate dehydrogenase 2 delays zebrafish erythroid maturation by conferring premature mitophagy

Mitochondria are the site of iron utilization, wherein imported iron is incorporated into heme or iron–sulfur clusters. Previously, we showed that a cytosolic siderophore, which resembles a bacterial siderophore, facilitates mitochondrial iron import in eukaryotes, including zebrafish. An evolutiona...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Davuluri, Gangarao, Song, Ping, Liu, Zhuoming, Wald, David, Sakaguchi, Takuya F., Green, Michael R., Devireddy, L.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801243/
https://ncbi.nlm.nih.gov/pubmed/26929344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600077113
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