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One-step self-assembled nanomicelles for improving the oral bioavailability of nimodipine

Our study aimed to develop a self-assembled nanomicelle for oral administration of nimodipine (NIM) with poor water solubility. Using Solutol(®) HS15, the NIM-loaded self-assembled nanomicelles displayed a near-spherical morphology with a narrow size distribution of 12.57±0.21 nm (polydispersity ind...

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Publicat a:Int J Nanomedicine
Autors principals: Luo, Jing-Wen, Zhang, Zhi-Rong, Gong, Tao, Fu, Yao
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801194/
https://ncbi.nlm.nih.gov/pubmed/27042060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S97834
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