Selective CDK7 inhibition with BS-181 suppresses cell proliferation and induces cell cycle arrest and apoptosis in gastric cancer

Cyclin-dependent kinase (CDK) family members have been considered as attractive therapeutic targets for cancer. In this study, we aim to investigate the anticancer effects of a selective CDK7 inhibitor, BS-181, in gastric cancer (GC) cell line. Human GC cells (BGC823) were cultured with or without B...

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Bibliografiska uppgifter
I publikationen:Drug Des Devel Ther
Huvudupphovsmän: Wang, Bo-Yong, Liu, Quan-Yan, Cao, Jun, Chen, Ji-Wei, Liu, Zhi-Su
Materialtyp: Artigo
Språk:Inglês
Publicerad: Dove Medical Press 2016
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801149/
https://ncbi.nlm.nih.gov/pubmed/27042010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S86317
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