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Genetic and structural analyses of cytochrome P450 hydroxylases in sex hormone biosynthesis: Sequential origin and subsequent coevolution

Biosynthesis of steroid hormones in vertebrates involves three cytochrome P450 hydroxylases, CYP11A1, CYP17A1 and CYP19A1, which catalyze sequential steps in steroidogenesis. These enzymes are conserved in the vertebrates, but their origin and existence in other chordate subphyla (Tunicata and Cepha...

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Podrobná bibliografie
Vydáno v:Mol Phylogenet Evol
Hlavní autoři: Goldstone, Jared V., Sundaramoorthy, Munirathinam, Zhao, Bin, Waterman, Michael R., Stegeman, John J., Lamb, David C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801120/
https://ncbi.nlm.nih.gov/pubmed/26432395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ympev.2015.09.012
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