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A combined series of Fgf9 and Fgf18 mutant alleles identifies unique and redundant roles in skeletal development

Fibroblast growth factor (FGF) signaling is a critical regulator of skeletal development. Fgf9 and Fgf18 are the only FGF ligands with identified functions in embryonic bone growth. Mice lacking Fgf9 or Fgf18 have distinct skeletal phenotypes; however, the extent of overlapping or redundant function...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Hung, Irene H., Schoenwolf, Gary C., Lewandoski, Mark, Ornitz, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801039/
https://ncbi.nlm.nih.gov/pubmed/26794256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2016.01.008
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