Recurrent deletions of IKZF1 in pediatric acute myeloid leukemia

IKAROS family zinc finger 1/IKZF1 is a transcription factor important in lymphoid differentiation, and a known tumor suppressor in acute lymphoid leukemia. Recent studies suggest that IKZF1 is also involved in myeloid differentiation. To investigate whether IKZF1 deletions also play a role in pediat...

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Publicat a:Haematologica
Autors principals: de Rooij, Jasmijn D.E., Beuling, Eva, van den Heuvel-Eibrink, Marry M., Obulkasim, Askar, Baruchel, André, Trka, Jan, Reinhardt, Dirk, Sonneveld, Edwin, Gibson, Brenda E.S., Pieters, Rob, Zimmermann, Martin, Zwaan, C. Michel, Fornerod, Maarten
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2015
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800704/
https://ncbi.nlm.nih.gov/pubmed/26069293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.124321
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