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Roles of endothelial A-type lamins in migration of T cells on and under endothelial layers

Stiff nuclei in cell-dense microenvironments may serve as distinct biomechanical cues for cell migration, but such a possibility has not been tested experimentally. As a first step addressing this question, we altered nuclear stiffness of endothelial cells (ECs) by reducing the expression of A-type...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Song, Kwang Hoon, Lee, Jaehyun, Park, HyoungJun, Kim, Hye Mi, Park, Jeehun, Kwon, Keon Woo, Doh, Junsang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800500/
https://ncbi.nlm.nih.gov/pubmed/26996137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23412
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