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Generation and transplantation of reprogrammed human neurons in the brain using 3D microtopographic scaffolds
Cell replacement therapy with human pluripotent stem cell-derived neurons has the potential to ameliorate neurodegenerative dysfunction and central nervous system injuries, but reprogrammed neurons are dissociated and spatially disorganized during transplantation, rendering poor cell survival, funct...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4800432/ https://ncbi.nlm.nih.gov/pubmed/26983594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10862 |
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