Generation and transplantation of reprogrammed human neurons in the brain using 3D microtopographic scaffolds

Cell replacement therapy with human pluripotent stem cell-derived neurons has the potential to ameliorate neurodegenerative dysfunction and central nervous system injuries, but reprogrammed neurons are dissociated and spatially disorganized during transplantation, rendering poor cell survival, funct...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Carlson, Aaron L., Bennett, Neal K., Francis, Nicola L., Halikere, Apoorva, Clarke, Stephen, Moore, Jennifer C., Hart, Ronald P., Paradiso, Kenneth, Wernig, Marius, Kohn, Joachim, Pang, Zhiping P., Moghe, Prabhas V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800432/
https://ncbi.nlm.nih.gov/pubmed/26983594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10862
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