Effect of Alzheimer's Disease Risk Variant rs3824968 at SORL1 on Regional Gray Matter Volume and Age-Related Interaction in Adult Lifespan

Sortilin receptor 1 (SORL1) is involved in cellular trafficking of amyloid precursor protein and plays an essential role in amyloid-beta peptide generation in Alzheimer disease (AD). The major A allele in a SORL1 single nucleotide polymorphism (SNP), rs3824968, is associated with an increased AD ris...

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Publicat a:Sci Rep
Autors principals: Huang, Chu-Chung, Liu, Mu-En, Kao, Hung-Wen, Chou, Kun-Hsien, Yang, Albert C., Wang, Ying-Hsiu, Chen, Tong-Ru, Tsai, Shih-Jen, Lin, Ching-Po
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800313/
https://ncbi.nlm.nih.gov/pubmed/26996954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23362
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