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NADPH Oxidase Inhibitor Apocynin Attenuates PCB153-Induced Thyroid Injury in Rats

PCBs, widespread endocrine disruptors, cause the disturbance of thyroid hormone (TH) homeostasis in humans and animals. However, the exact mechanism of thyroid dysfunction caused by PCBs is still unknown. In order to clarify the hypotheses that NADPH oxidase (NOX) and subsequent NF-κB pathway may pl...

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Bibliografske podrobnosti
izdano v:Int J Endocrinol
Main Authors: Abliz, Ablikim, Chen, Chen, Deng, Wenhong, Wang, Weixing, Sun, Rongze
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800090/
https://ncbi.nlm.nih.gov/pubmed/27047545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8354745
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