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The early effect of sunitinib on insulin clearance in patients with metastatic renal cell carcinoma

AIMS: In patients with diabetes treated with sunitinib symptomatic hypoglycaemia has been reported. To explore the mechanism of this adverse effect we performed a prospective study to investigate the effect of sunitinib on insulin concentration, insulin clearance and insulin sensitivity. METHODS: We...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Thijs, Anna Maria J., Tack, Cees J., van der Graaf, Winette T. A., Rongen, Gerard A., van Herpen, Carla M. L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799938/
https://ncbi.nlm.nih.gov/pubmed/26447463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12797
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