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Influence of chronic kidney disease on anticoagulation levels and bleeding after primary percutaneous coronary intervention in patients treated with unfractionated heparin

Unfractionated heparin (UFH) plasma protein binding and elimination might be impaired in patients with chronic kidney disease (CKD—defined as creatinine clearance <60 ml/min). It is currently unknown at which UFH bolus dose persistent prolongation of activated partial thromboplastin time (aPTT) o...

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Pubblicato in:J Thromb Thrombolysis
Autori principali: Kikkert, Wouter J., van Brussel, Peter M., Damman, Peter, Claessen, Bimmer E., van Straalen, Jan P., Vis, Marije M., Baan, Jan, Koch, Karel T., Peters, Ron J., de Winter, Robbert J., Piek, Jan J., Tijssen, Jan G. P., Henriques, Jose P. S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799790/
https://ncbi.nlm.nih.gov/pubmed/26238770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11239-015-1255-x
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