TNF-alpha promotes lymphangiogenesis and lymphatic metastasis of gallbladder cancer through the ERK1/2/AP-1/VEGF-D pathway

BACKGROUND: Tumor necrosis factor-alpha (TNF-α), a key player in cancer-related inflammation, was recently demonstrated to be involved in the lymphatic metastasis of gallbladder cancer (GBC). Vascular endothelial growth factor D (VEGF-D) is a key lymphangiogenic factor that is associated with lympha...

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Библиографические подробности
Опубликовано в: :BMC Cancer
Главные авторы: Hong, HaiJie, Jiang, Lei, Lin, YanFei, He, CaiLong, Zhu, GuangWei, Du, Qiang, Wang, XiaoQian, She, FeiFei, Chen, YanLing
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2016
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799527/
https://ncbi.nlm.nih.gov/pubmed/26992854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2259-4
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