Decreased ovarian reserve, dysregulation of mitochondrial biogenesis, and increased lipid peroxidation in female mouse offspring exposed to an obesogenic maternal diet

Maternal diet during pregnancy influences the later life reproductive potential of female offspring. We investigate the molecular mechanisms underlying the depletion of ovarian follicular reserve in young adult females following exposure to obesogenic diet in early life. Furthermore, we explore the...

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Bibliographic Details
Published in:FASEB J
Main Authors: Aiken, Catherine E., Tarry-Adkins, Jane L., Penfold, Naomi C., Dearden, Laura, Ozanne, Susan E.
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2016
Subjects:
Research Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799509/
https://ncbi.nlm.nih.gov/pubmed/26700734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-280800
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