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Decreased ovarian reserve, dysregulation of mitochondrial biogenesis, and increased lipid peroxidation in female mouse offspring exposed to an obesogenic maternal diet

Maternal diet during pregnancy influences the later life reproductive potential of female offspring. We investigate the molecular mechanisms underlying the depletion of ovarian follicular reserve in young adult females following exposure to obesogenic diet in early life. Furthermore, we explore the...

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Veröffentlicht in:FASEB J
Hauptverfasser: Aiken, Catherine E., Tarry-Adkins, Jane L., Penfold, Naomi C., Dearden, Laura, Ozanne, Susan E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799509/
https://ncbi.nlm.nih.gov/pubmed/26700734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-280800
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