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Cloning, characterization, and expression of a cDNA encoding an inducible nitric oxide synthase from the human chondrocyte.

Incubation of human articular chondrocytes with interleukin 1 beta results in the time-dependent expression of nitric oxide (NO) synthase. We report here the isolation of a cDNA clone which encodes a protein of 1153 amino acids with a molecular mass of 131,213 Da and a calculated isoelectric point o...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Charles, I G, Palmer, R M, Hickery, M S, Bayliss, M T, Chubb, A P, Hall, V S, Moss, D W, Moncada, S
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1993
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47994/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504305/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.23.11419
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