cMET inhibitor crizotinib impairs angiogenesis and reduces tumor burden in the C3(1)-Tag model of basal-like breast cancer

Epidemiologic studies have associated obesity with increased risk of the aggressive basal-like breast cancer (BBC) subtype. Hepatocyte growth factor (HGF) signaling through its receptor, cMET, is elevated in obesity and is a pro-tumorigenic pathway strongly associated with BBC. We previously reporte...

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Detalhes bibliográficos
Publicado no:Springerplus
Main Authors: Cozzo, Alyssa J., Sundaram, Sneha, Zattra, Ottavia, Qin, Yuanyuan, Freemerman, Alex J., Essaid, Luma, Darr, David B., Montgomery, Stephanie A., McNaughton, Kirk K., Ezzell, J. Ashley, Galanko, Joseph A., Troester, Melissa A., Makowski, Liza
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799044/
https://ncbi.nlm.nih.gov/pubmed/27057482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-016-1920-3
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