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cMET inhibitor crizotinib impairs angiogenesis and reduces tumor burden in the C3(1)-Tag model of basal-like breast cancer

Epidemiologic studies have associated obesity with increased risk of the aggressive basal-like breast cancer (BBC) subtype. Hepatocyte growth factor (HGF) signaling through its receptor, cMET, is elevated in obesity and is a pro-tumorigenic pathway strongly associated with BBC. We previously reporte...

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Bibliografski detalji
Izdano u:Springerplus
Glavni autori: Cozzo, Alyssa J., Sundaram, Sneha, Zattra, Ottavia, Qin, Yuanyuan, Freemerman, Alex J., Essaid, Luma, Darr, David B., Montgomery, Stephanie A., McNaughton, Kirk K., Ezzell, J. Ashley, Galanko, Joseph A., Troester, Melissa A., Makowski, Liza
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799044/
https://ncbi.nlm.nih.gov/pubmed/27057482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-016-1920-3
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