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Environmental enrichment facilitates cocaine-cue extinction, deters reacquisition of cocaine self-administration, and alters AMPAR GluA1 expression and phosphorylation

This study investigated the combination of environmental enrichment (EE) with cocaine-cue extinction training on reacquisition of cocaine self-administration. Rats were trained under a second-order schedule for which responses were maintained by cocaine injections and cocaine-paired stimuli. During...

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Detalhes bibliográficos
Publicado no:Addict Biol
Main Authors: Gauthier, Jamie M., Lin, Amy, Nic Dhonnchadha, Bríd Á., Spealman, Roger D., Man, Heng-Ye, Kantak, Kathleen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798903/
https://ncbi.nlm.nih.gov/pubmed/26384129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12313
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