Cancer Stem Cell-Based Models of Colorectal Cancer Reveal Molecular Determinants of Therapy Resistance

Colorectal cancer (CRC) therapy mainly relies on the use of conventional chemotherapeutic drugs combined, in a subset of patients, with epidermal growth factor receptor [EGFR]-targeting agents. Although CRC is considered a prototype of a cancer stem cell (CSC)-driven tumor, the effects of both conve...

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Bibliografiska uppgifter
I publikationen:Stem Cells Transl Med
Huvudupphovsmän: De Angelis, Maria Laura, Zeuner, Ann, Policicchio, Eleonora, Russo, Giorgio, Bruselles, Alessandro, Signore, Michele, Vitale, Sara, De Luca, Gabriele, Pilozzi, Emanuela, Boe, Alessandra, Stassi, Giorgio, Ricci-Vitiani, Lucia, Amoreo, Carla Azzurra, Pagliuca, Alfredo, Francescangeli, Federica, Tartaglia, Marco, De Maria, Ruggero, Baiocchi, Marta
Materialtyp: Artigo
Språk:Inglês
Publicerad: AlphaMed Press 2016
Ämnen:
Cancer Stem Cells
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798739/
https://ncbi.nlm.nih.gov/pubmed/26956206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0214
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