The Drosophila melanogaster flightless-I gene involved in gastrulation and muscle degeneration encodes gelsolin-like and leucine-rich repeat domains and is conserved in Caenorhabditis elegans and humans.

Mutations at the flightless-I locus (fliI) of Drosophila melanogaster cause flightlessness or, when severe, incomplete cellularization during early embryogenesis, with subsequent abnormalities in mesoderm invagination and in gastrulation. After chromosome walking, deficiency mapping, and transgenic...

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Detalhes bibliográficos
Main Authors: Campbell, H D, Schimansky, T, Claudianos, C, Ozsarac, N, Kasprzak, A B, Cotsell, J N, Young, I G, de Couet, H G, Miklos, G L
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC47987/
https://ncbi.nlm.nih.gov/pubmed/8248259
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