Evaluation of High Resolution Melting for MTHFR C677T Genotyping in Congenital Heart Disease

BACKGROUND: High resolution melting (HRM) is a simple, flexible and low-cost mutation screening technique. The methylenetetrahydrofolate reductase (MTHFR) gene encoding a critical enzyme, potentially affects susceptibility to some congenital defects like congenital heart disease (CHD). We evaluate t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wang, Ying, Zhang, Haiyan, Yue, Shuying, Zhang, Kun, Wang, Hui, Dong, Rui, Yang, Xiaomeng, Liu, Yi, Ma, Yanhui
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798616/
https://ncbi.nlm.nih.gov/pubmed/26990189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151140
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