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Calcitonin Gene-Related Peptide Modulates Heat Nociception in the Human Brain - An fMRI Study in Healthy Volunteers

BACKGROUND: Intravenous infusion of calcitonin-gene-related-peptide (CGRP) provokes headache and migraine in humans. Mechanisms underlying CGRP-induced headache are not fully clarified and it is unknown to what extent CGRP modulates nociceptive processing in the brain. To elucidate this we recorded...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Asghar, Mohammad Sohail, Becerra, Lino, Larsson, Henrik B. W., Borsook, David, Ashina, Messoud
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798403/
https://ncbi.nlm.nih.gov/pubmed/26990646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150334
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