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Resistance to Novel Antiandrogen Therapies in Metastatic Castration-Resistant Prostate Cancer

Despite the introduction of novel therapies that maximally decrease androgen-receptor (AR) signaling activity, metastatic castration-resistant prostate cancer (mCRPC) remains a lethal disease. Even though abiraterone and enzalutamide represent breakthroughs in the treatment of mCRPC and have demonst...

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Bibliographic Details
Published in:Clin Med Insights Oncol
Main Authors: Boudadi, Karim, Antonarakis, Emmanuel S.
Format: Artigo
Language:Inglês
Published: SAGE Publications 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798019/
https://ncbi.nlm.nih.gov/pubmed/27013902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CMO.Ss34534
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