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Erythropoietin receptor signals both proliferation and erythroid-specific differentiation.

Ectopic expression of the erythropoietin receptor (EPO-R) in Ba/F3, an interleukin 3-dependent progenitor cell line, confers EPO-dependent cell growth. To examine whether the introduced EPO-R could affect differentiation, we isolated Ba/F3-EPO-R subclones in interleukin 3 and assayed for the inducti...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Liboi, E, Carroll, M, D'Andrea, A D, Mathey-Prevot, B
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47980/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8248252/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.23.11351
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