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Influence of immunoglobulin isotype on therapeutic antibody function

Monoclonal antibody (mAb) therapeutics are revolutionizing cancer treatment; however, not all tumors respond, and agent optimization is essential to improve outcome. It has become clear over recent years that isotype choice is vital to therapeutic success with agents that work through different mech...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Beers, Stephen A., Glennie, Martin J., White, Ann L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4797141/
https://ncbi.nlm.nih.gov/pubmed/26764357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-09-625343
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