Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans.

Direct gene transfer offers the potential to introduce DNA encoding therapeutic proteins to treat human disease. Previously, gene transfer in humans has been achieved by a cell-mediated ex vivo approach in which cells from the blood or tissue of patients are genetically modified in the laboratory an...

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Detalhes bibliográficos
Main Authors: Nabel, G J, Nabel, E G, Yang, Z Y, Fox, B A, Plautz, G E, Gao, X, Huang, L, Shu, S, Gordon, D, Chang, A E
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC47971/
https://ncbi.nlm.nih.gov/pubmed/8248244
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