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PTTG/securin activates expression of p53 and modulates its function
BACKGROUND: Pituitary tumor transforming gene (PTTG) is a novel oncogene that is expressed abundantly in most tumors. Overexpression of PTTG induces cellular transformation and promotes tumor formation in nude mice. PTTG has been implicated in various cellular processes including sister chromatid se...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC479695/ https://ncbi.nlm.nih.gov/pubmed/15242522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-3-18 |
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