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PTTG/securin activates expression of p53 and modulates its function

BACKGROUND: Pituitary tumor transforming gene (PTTG) is a novel oncogene that is expressed abundantly in most tumors. Overexpression of PTTG induces cellular transformation and promotes tumor formation in nude mice. PTTG has been implicated in various cellular processes including sister chromatid se...

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Bibliografiske detaljer
Main Authors: Hamid, Tariq, Kakar, Sham S
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC479695/
https://ncbi.nlm.nih.gov/pubmed/15242522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-3-18
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