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Spines slow down dendritic chloride diffusion and affect short-term ionic plasticity of GABAergic inhibition

Cl(−) plays a crucial role in neuronal function and synaptic inhibition. However, the impact of neuronal morphology on the diffusion and redistribution of intracellular Cl(−) is not well understood. The role of spines in Cl(−) diffusion along dendritic trees has not been addressed so far. Because me...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mohapatra, Namrata, Tønnesen, Jan, Vlachos, Andreas, Kuner, Thomas, Deller, Thomas, Nägerl, U. Valentin, Santamaria, Fidel, Jedlicka, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796789/
https://ncbi.nlm.nih.gov/pubmed/26987404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23196
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