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ZnT4 (SLC30A4)-null (“lethal milk”) mice have defects in mammary gland secretion and hallmarks of precocious involution during lactation

During lactation, highly specialized secretory mammary epithelial cells (MECs) produce and secrete huge quantities of nutrients and nonnutritive factors into breast milk. The zinc (Zn) transporter ZnT4 (SLC30A4) transports Zn into the trans-Golgi apparatus for lactose synthesis, and across the apica...

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Bibliografske podrobnosti
izdano v:Am J Physiol Regul Integr Comp Physiol
Main Authors: McCormick, Nicholas H., Lee, Sooyeon, Hennigar, Stephen R., Kelleher, Shannon L.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796636/
https://ncbi.nlm.nih.gov/pubmed/26538236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00315.2014
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