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Cross talk between AT(1) receptors and Toll-like receptor 4 in microglia contributes to angiotensin II-derived ROS production in the hypothalamic paraventricular nucleus

ANG II is thought to increase sympathetic outflow by increasing oxidative stress and promoting local inflammation in the paraventricular nucleus (PVN) of the hypothalamus. However, the relative contributions of inflammation and oxidative stress to sympathetic drive remain poorly understood, and the...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Heart Circ Physiol
Main Authors: Biancardi, Vinicia Campana, Stranahan, Alexis M., Krause, Eric G., de Kloet, Annette D., Stern, Javier E.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796625/
https://ncbi.nlm.nih.gov/pubmed/26637556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00247.2015
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