Effects of the PPAR-β/δ agonist GW0742 during resuscitated porcine septic shock

BACKGROUND: In un-resuscitated rodent models of septic shock, the peroxisome proliferator-activated receptor-β/δ (PPAR-β/δ) agonist GW0742 improved visceral organ function. Therefore, we tested the hypothesis whether GW0742 would attenuate kidney injury during long-term, resuscitated, porcine polymi...

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Vydáno v:Intensive Care Med Exp
Hlavní autoři: Wepler, Martin, Hafner, Sebastian, Scheuerle, Angelika, Reize, Matthias, Gröger, Michael, Wagner, Florian, Simon, Florian, Matallo, José, Gottschalch, Frank, Seifritz, Andrea, Stahl, Bettina, Matejovic, Martin, Kapoor, Amar, Möller, Peter, Calzia, Enrico, Georgieff, Michael, Wachter, Ulrich, Vogt, Josef A, Thiemermann, Christoph, Radermacher, Peter, McCook, Oscar
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2013
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796150/
https://ncbi.nlm.nih.gov/pubmed/26266797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2197-425X-1-9
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