Llwytho...
Systems Pharmacology and Rational Polypharmacy: Nitric Oxide−Cyclic GMP Signaling Pathway as an Illustrative Example and Derivation of the General Case
Impaired nitric oxide (NO˙)-cyclic guanosine 3', 5'-monophosphate (cGMP) signaling has been observed in many cardiovascular disorders, including heart failure and pulmonary arterial hypertension. There are several enzymatic determinants of cGMP levels in this pathway, including soluble gua...
Wedi'i Gadw mewn:
Cyhoeddwyd yn: | PLoS Comput Biol |
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Prif Awduron: | , , , |
Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
Public Library of Science
2016
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4795786/ https://ncbi.nlm.nih.gov/pubmed/26985825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004822 |
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