The Extracellular and Cytoplasmic Domains of Syndecan Cooperate Postsynaptically to Promote Synapse Growth at the Drosophila Neuromuscular Junction

The heparan sulfate proteoglycan (HSPG) Syndecan (Sdc) is a crucial regulator of synapse development and growth in both vertebrates and invertebrates. In Drosophila, Sdc binds via its extracellular heparan sulfate (HS) sidechains to the receptor protein tyrosine phosphatase LAR to promote the morpho...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nguyen, Margaret U., Kwong, Jereen, Chang, Julia, Gillet, Victoria G., Lee, Rachel M., Johnson, Karl Gregory
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795781/
https://ncbi.nlm.nih.gov/pubmed/26987116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151621
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