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Characterization of Disease-Associated Mutations in Human Transmembrane Proteins

Transmembrane protein coding genes are commonly associated with human diseases. We characterized disease causing mutations and natural polymorphisms in transmembrane proteins by mapping missense genetic variations from the UniProt database on the transmembrane protein topology listed in the Human Tr...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Molnár, János, Szakács, Gergely, Tusnády, Gábor E.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795776/
https://ncbi.nlm.nih.gov/pubmed/26986070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151760
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