Amelioration of Diabetic Mouse Nephropathy by Catalpol Correlates with Down-Regulation of Grb10 Expression and Activation of Insulin-Like Growth Factor 1 / Insulin-Like Growth Factor 1 Receptor Signaling

Growth factor receptor-bound protein 10 (Grb10) is an adaptor protein that can negatively regulate the insulin-like growth factor 1 receptor (IGF-1R). The IGF1-1R pathway is critical for cell growth and apoptosis and has been implicated in kidney diseases; however, it is still unknown whether Grb10...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Yang, Shasha, Deng, Huacong, Zhang, Qunzhou, Xie, Jing, Zeng, Hui, Jin, Xiaolong, Ling, Zixi, Shan, Qiaoyun, Liu, Momo, Ma, Yuefei, Tang, Juan, Wei, Qianping
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795681/
https://ncbi.nlm.nih.gov/pubmed/26986757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151857
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