Duplicated copy of CHRNA7 increases risk and worsens prognosis of COPD and lung cancer

Recent genome-wide association studies implicated that the nicotinic acetylcholine receptors (nAChRs) are common susceptible genes of two contextual diseases: chronic obstructive pulmonary disease (COPD) and lung cancer. We aimed to test whether the copy number variations (CNVs) in nAChRs have hered...

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Bibliografiske detaljer
Udgivet i:Eur J Hum Genet
Main Authors: Yang, Lei, Lu, Xiaoxiao, Qiu, Fuman, Fang, Wenxiang, Zhang, Lisha, Huang, Dongsheng, Xie, Chenli, Zhong, Nanshan, Ran, Pixin, Zhou, Yifeng, Lu, Jiachun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795111/
https://ncbi.nlm.nih.gov/pubmed/25407004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2014.229
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